![]() Clinicians should be aware of the multi-system complications that are associated with CP and which may present significant diagnostic challenges given that many children with CP communicate non-verbally. Additionally, several biomarkers hold promise in assisting with long-term monitoring. MOD in CP has not yet been quantified and a scoring system may prove useful in allowing advanced clinical planning and follow-up of children with CP. It may also contribute to an improved understanding of the etiology and thus may have an implication in prevention, interventional methods and therapies. Assessment of multi-organ function may help to prevent complications in later childhood or adulthood. Therefore, CP should not be seen as an unchanging disorder caused by a solitary insult but rather, as a condition which evolves over time. Alongside this, there has been increasing recognition of the multi-organ dysfunction (MOD) associated with CP, in particular in children with higher levels of motor impairment. Our understanding of the underlying cause of CP has developed significantly, with areas such as inflammation, epigenetics and genetic susceptibility to subsequent insults providing new insights. Each case requires detailed consideration of etiology. CP is an umbrella term for a heterogenous condition and is, therefore, descriptive rather than a diagnosis.
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